Expanded Somatic Mutation Spectrum of MED12 Gene in Uterine Leiomyomas of Saudi Arabian Women

MED12, a subunit of mediator complex genes is known to harbor genetic mutations, (mostly in exon 2), causal to the genesis of uterine leiomyomas among Caucasian, African American, and Asian women. However, the precise relationship between genetic mutations vs. protein or disease phenotype is not wel...

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Auteurs principaux:	Ghada M. A. Ajabnoor, Nesma Amin Mohammed, Babajan Banaganapalli, Layla Saleh Abdullah, Ola Nabeel Bondagji, Nisma Mansouri, Nora Naif Sahly, Venkatesh Vaidyanathan, Nabeel Bondagji, Ramu Elango, Noor Ahmad Shaik
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2018-12-01
Collection:	Frontiers in Genetics
Sujets:	uterine leiomyomas MED12 gene Arab women uterine somatic mutations Luteinizing hormone
Accès en ligne:	https://www.frontiersin.org/article/10.3389/fgene.2018.00552/full
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