A Case of Metastatic Castration‐Resistant Prostate Cancer With RAD54L Mutation Responding to Niraparib

ABSTRACT Introduction A certain proportion of prostate cancers have alterations in homologous recombination repair (HRR)‐ related genes. poly ADP‐ribose polymerase (PARP) inhibitors have been approved for metastatic castration‐resistant prostate cancer (mCRPC) with mutations in the BRCA1/2 gene. For...

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Autors principals:	Yusuke Sato, Yoichi Fujii, Masaki Nakamura, Chiharu Tanai, Yuta Yamada, Kousuke Watanabe, Hidenori Kage, Kuniko Sunami, Katsutoshi Oda, Haruki Kume
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2025-11-01
Col·lecció:	IJU Case Reports
Matèries:	genomic medicine niraparib poly (ADP‐ribose) polymerase inhibitors precision medicine prostatic neoplasms
Accés en línia:	https://doi.org/10.1002/iju5.70093
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