Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors

Background Pediatric brain tumors are the leading cause of cancer death in children with an urgent need for innovative therapies. Glypican 2 (GPC2) is a cell surface oncoprotein expressed in neuroblastoma for which targeted immunotherapies have been developed. This work aimed to characterize GPC2 ex...

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Bibliografiske detaljer

Principais autores:	David M Barrett, Daniel Martinez, Tiffany Smith, Jessica B Foster, Crystal Griffin, Jo Lynne Rokita, Allison Stern, Cameron Brimley, Komal Rathi, Maria V Lane, Samantha N Buongervino, Peter J Madsen, Alberto Delaidelli, Poul H Sorensen, Robert J Wechsler-Reya, Katalin Karikó, Phillip B Storm, Adam C Resnick, John M Maris, Kristopher R Bosse
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMJ Publishing Group 2022-09-01
Serier:	Journal for ImmunoTherapy of Cancer
Online adgang:	https://jitc.bmj.com/content/10/9/e004450.full
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