A Pangenomic Approach to Improve Population Genetics Analysis and Reference Bias in Underrepresented Middle Eastern and Horn of Africa Populations

Genomics plays a crucial role in addressing health disparities, yet most studies rely on the hg38 linear reference genome, limiting the potential of pangenomic approaches, particularly for underrepresented populations. In this study, we focus on characterising East African populations, particularly...

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Autori principali:	Adrien Oliva, Rachel Foare, Peter Campbell, Natalie A. Twine, Denis C. Bauer, Angad Singh Johar
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2025-04-01
Serie:	Biomolecules
Soggetti:	pangenomics variation graph reference bias genomic medicine population genetics underrepresented populations
Accesso online:	https://www.mdpi.com/2218-273X/15/4/582
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