Hydrophilic But Not Hydrophobic Surfactant Protein Genetic Variants Are Associated With Severe Acute Respiratory Syncytial Virus Infection in Children

Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection-related hospitalization in the first year of life. Surfactant dysfunction is central to pathophysiologic mechanisms of various pulmonary diseases including RSV. We hypothesized that RSV severity is associated...

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Autors principals:	Lynnlee C. Depicolzuane, Catherine M. Roberts, Neal J. Thomas, Keenan Anderson-Fears, Dajiang Liu, João Paulo Pereira Barbosa, Felipe Rodrigues Souza, André Silva Pimentel, Joanna Floros, Chintan K. Gandhi
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-07-01
Col·lecció:	Frontiers in Immunology
Matèries:	respiratory sycytial virus surfacant protein genetic variant single nucelotide polymorphisms SFTPA1 SFTPA2 SFTPB
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.922956/full
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