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Spinal Cord Stimulation Modulates Supraspinal Centers of the Descending Antinociceptive System in Rats with Unilateral Spinal Nerve Injury

Background The descending antinociceptive system (DAS) is thought to play crucial roles in the antinociceptive effect of spinal cord stimulation (SCS), especially through its serotonergic pathway. The nucleus raphe magnus (NRM) in the rostral ventromedial medulla is a major source of serotonin [5-hy...

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Autori principali: Toshiharu Tazawa, Yoshinori Kamiya, Ayako Kobayashi, Kensuke Saeki, Masahito Takiguchi, Yusuke Nakahashi, Hironobu Shinbori, Kengo Funakoshi, Takahisa Goto
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publishing 2015-06-01
Serie:Molecular Pain
Accesso online:https://doi.org/10.1186/s12990-015-0039-9
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