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Neoantigens as potential vaccines in hepatocellular carcinoma

Background Neoantigens, new immunogenic sequences arising from tumor mutations, have been associated with response to immunotherapy and are considered potential targets for vaccination. Hepatocellular carcinoma (HCC) is a moderately mutated tumor, where the neoantigen repertoire has not been investi...

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Principais autores: Kathrin Heim, Maike Hofmann, Robert Thimme, Marta Ruiz, Pablo Sarobe, Sandra Hervás-Stubbs, Bruno Sangro, Luigi Buonaguro, Beatrice Cavalluzzo, Angela Mauriello, Maria Tagliamonte, David Repáraz, Enric Vercher, Diana Llopiz, Leyre Silva, Belén Aparicio, Josune Egea, Ibon Tamayo-Uria, Jorge García-Balduz, Carla Castro, Mercedes Iñarrairaegui, Charlotte Rohrer, Catrin Tauber
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2022-02-01
coleção:Journal for ImmunoTherapy of Cancer
Acesso em linha:https://jitc.bmj.com/content/10/2/e003978.full
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