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HCMV as an Oncomodulatory Virus in Ovarian Cancer: Implications of Viral Strain Heterogeneity, Immunomodulation, and Inflammation on the Tumour Microenvironment and Ovarian Cancer Progression

The complex relationship between human cytomegalovirus (HCMV) and cancer has been of interest since the 1960s. As a highly prevalent human β-herpesvirus, HCMV establishes lifelong latency in CD34+ myeloid progenitor cells and has been implicated as an oncomodulatory virus in various cancers, includi...

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Principais autores: Chrissie Giatrakis, Apriliana E. R. Kartikasari, Thomas A. Angelovich, Katie L. Flanagan, Melissa J. Churchill, Clare L. Scott, Srinivasa Reddy Telukutla, Magdalena Plebanski
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-12-01
coleção:Biomolecules
Assuntos:
human cytomegalovirus
ovarian cancer
cancer progression
immunomodulation
inflammation
tumour microenvironment
Acesso em linha:https://www.mdpi.com/2218-273X/15/12/1685
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