Diverse and reprogrammable mechanisms of malignant cell transformation in lymphocytes: pathogenetic insights and translational implications

While normal B- and T-lymphocytes require antigenic ligands to become activated via their B- and T-cell receptors (BCR and TCR, respectively), B- and T-cell lymphomas show the broad spectrum of cell activation mechanisms regarding their dependence on BCR or TCR signaling, including loss of such depe...

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Auteurs principaux:	Mariusz A. Wasik, Patricia M. Kim, Reza Nejati
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2024-04-01
Collection:	Frontiers in Oncology
Sujets:	B-cell lymphoma T-cell lymphoma pathogenic signaling plasticity dedifferentiation transdifferentiation
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1383741/full
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