A novel hACE2 knock-in mouse model recapitulates pulmonary and intestinal SARS-CoV-2 infection

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission is responsible for the coronavirus disease 2019 (COVID-19) pandemic. SARS-CoV-2 uses the angiotensin-converting enzyme 2 (ACE2) receptor to enter the host, and the gastrointestinal tract is a potential infection site as this r...

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Autori principali:	Xiaoyang Zhou, Weiyang Sun, Yu Zhang, Hongjing Gu, Ruixuan Wang, Peng Xie, Yunkai Zhu, Minyue Qiu, Xiaoyan Ding, Hui Wang, Yuwei Gao, Jintao Li
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2023-06-01
Serie:	Frontiers in Microbiology
Soggetti:	mouse model intestinal infection SARS-CoV-2 immune cells pneumonia
Accesso online:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1175188/full
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