A two‐sample Mendelian randomization study and mediation analysis exploring the link between cathepsins and epilepsy

Abstract Objective This study aims to investigate the causal relationship between cathepsins and epilepsy, using Mendelian randomization (MR) and mediation analysis. Methods Publicly accessible summary statistics on epilepsy were obtained from FinnGen and the International League Against Epilepsy Co...

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Bibliographic Details

Main Authors:	Huaiyu Sun, Di Ma, Wuqiong Zhang, Shuai Hou, Zhiqing Chen, Xuewei Li, Hongmei Meng, Daguang Zhang
Format:	Artigo
Language:	Inglês
Published:	Wiley 2026-02-01
Series:	Epilepsia Open
Subjects:	bidirectional causal effects cathepsins epilepsy mediation analysis Mendelian randomization
Online Access:	https://doi.org/10.1002/epi4.70056
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