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Estradiol reduces ferrous citrate complex-induced NOS2 up-regulation in cerebral endothelial cells by interfering the nuclear factor kappa B transactivation through an estrogen receptor β-mediated pathway.

Hemorrhagic stroke caused leakage of red blood cells which converts to hemoglobin, heme, and iron accumulated at the lesions. High concentration of ferrous iron from subarachnoid hemorrhage (SAH) induced cerebral vasospasm. Using the two-hemorrhage SAH model in rats, we previously demonstrated that...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li-Ching Chen, Wen-Sen Lee
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2013-01-01
Cyfres:PLoS ONE
Mynediad Ar-lein:http://europepmc.org/articles/PMC3871628?pdf=render
Tagiau: Ychwanegu Tag
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