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Efficient and selective isotopic labeling of hemes to facilitate the study of multiheme proteins

Specific isotopic labeling of hemes provides a unique opportunity to characterize the structure and function of heme-proteins. Unfortunately, current methods do not allow efficient labeling in high yields of multiheme cytochromes c, which are of great biotechnological interest. Here, a method for pr...

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Autori principali: Bruno M. Fonseca, Ming Tien, Mario Rivera, Liang Shi, Ricardo O. Louro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis Group 2012-04-01
Serie:BioTechniques
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Accesso online:https://www.future-science.com/doi/10.2144/000113859
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