Pseudomonas aeruginosa C-Terminal Processing Protease CtpA Assembles into a Hexameric Structure That Requires Activation by a Spiral-Shaped Lipoprotein-Binding Partner

ABSTRACT Pseudomonas aeruginosa CtpA is a carboxyl-terminal processing protease that partners with the outer membrane lipoprotein LbcA to degrade at least five cell wall-associated proteins, four of which are cell wall hydrolases. This activity plays an important role in supporting P. aeruginosa vir...

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Hauptverfasser:	Hao-Chi Hsu, Michelle Wang, Amanda Kovach, Andrew J. Darwin, Huilin Li
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2022-02-01
Schriftenreihe:	mBio
Schlagworte:	C-terminal processing protease cell wall cryo-EM Pseudomonas aeruginosa structural biology
Online-Zugang:	https://journals.asm.org/doi/10.1128/mbio.03680-21
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