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Uniformity under in vitro conditions: Changes in the phenotype of cancer cell lines derived from different medulloblastoma subgroups.

Medulloblastoma comprises four main subgroups (WNT, SHH, Group 3 and Group 4) originally defined by transcriptional profiling. In primary medulloblastoma tissues, these groups are thought to be distinguishable using the immunohistochemical detection of β-catenin, filamin A, GAB1 and YAP1 protein mar...

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Principais autores: Petr Chlapek, Karel Zitterbart, Leos Kren, Lenka Filipova, Jaroslav Sterba, Renata Veselska
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2017-01-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC5322931?pdf=render
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