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Knockdown of LINC00963 targets miR-1252-5p to reduce inflammatory levels and ECM degradation in nucleus pulposus cells of IDD

Abstract Background In middle-aged and older adults, intervertebral disc degeneration (IDD) is a major cause of chronic low back pain and disability. This pathological process is closely linked to the activation of inflammatory factors resulting from an imbalance in extracellular matrix (ECM) metabo...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Chao Wei, Jiacheng Li, Gang-Gang Wang, Qingfeng Zhang
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2026-04-01
Rangatū:BMC Musculoskeletal Disorders
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s12891-026-09848-0
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