Genetically predicted telomere length is associated with clonal somatic copy number alterations in peripheral leukocytes.

Telomeres are DNA-protein structures at the ends of chromosomes essential in maintaining chromosomal stability. Observational studies have identified associations between telomeres and elevated cancer risk, including hematologic malignancies; but biologic mechanisms relating telomere length to cance...

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Detalhes bibliográficos

Principais autores:	Derek W Brown, Shu-Hong Lin, Po-Ru Loh, Stephen J Chanock, Sharon A Savage, Mitchell J Machiela
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2020-10-01
Colecção:	PLoS Genetics
Acesso em linha:	https://doi.org/10.1371/journal.pgen.1009078
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