Targeted deletion of the pancreatic β-cell oxytocin receptor and its effects on metabolic regulation and β-cell health

The neuropeptide oxytocin (OXT) and its receptor (OXTR) have been shown to play an important role in glucose metabolism, and pancreatic islets express this ligand and receptor. In the current study, OXTR expression was identified in α-, β-, and δ-cells of the pancreatic islet by in situ RNA hybridiz...

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Principais autores:	Armando J. Mendez, Angela Szeto, Maria Boulina, Jesica Westwright, Hafsha Rahman, Sarah Abushamma, Riley Schneider, Philip M. McCabe
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-12-01
coleção:	Frontiers in Endocrinology
Assuntos:	oxytocin receptor oxytocin knockout mouse pancreatic islets β-cells insulin
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fendo.2024.1465818/full
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