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Prospective Evaluation of Malignancy in 17,708 Patients Randomized to Ezetimibe Versus Placebo

Background: An increased risk of malignancy was reported with simvastatin/ezetimibe in 1,873 patients in the SEAS (Simvastatin and Ezetimibe in Aortic Stenosis) trial. Objectives: The purpose of this study was to clarify this unexpected finding in a larger sample size of patients stabilized after ac...

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Principais autores: Robert P. Giugliano, MD, SM, Baris Gencer, MD, Stephen D. Wiviott, MD, Jeong-Gun Park, PHD, Charles S. Fuchs, MD, MPH, Wolfram Goessling, MD, PHD, Thomas A. Musliner, MD, Andrew M. Tershakovec, MD, MPH, Michael A. Blazing, MD, Robert Califf, MD, Christopher P. Cannon, MD, Eugene Braunwald, MD
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-09-01
coleção:JACC. CardioOncology
Assuntos:
acute coronary syndromes
cancer
ezetimibe
lipid-lowering therapy
lipids
malignancy
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2666087320301708
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