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Astrocytes Regulate Neuronal Network Burst Frequency Through NMDA Receptors in a Species- and Donor-Specific Manner

Background: Development of synaptic activity is a key neuronal characteristic that relies largely on interactions between neurons and astrocytes. Although astrocytes have known roles in regulating synaptic function and malfunction, the use of human- or donor-specific astrocytes in disease models is...

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Principais autores: Noora Räsänen, Jari Tiihonen, Marja Koskuvi, Šárka Lehtonen, Nelli Jalkanen, Nelli Karmila, Isabelle Weert, Olli Vaurio, Ilkka Ojansuu, Markku Lähteenvuo, Olli Pietiläinen, Jari Koistinaho
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-07-01
coleção:Biological Psychiatry Global Open Science
Assuntos:
Astrocytes
Induced pluripotent stem cells
Microelectrode array
Neurons
NMDA receptors
Schizophrenia
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2667174324000260
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