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Nucleophilic Arylation of Halopurines Facilitated by Brønsted Acid in Fluoroalcohol

Various aryl-substituted purine derivatives were synthesized through the direct arylation of halopurines with aromatic compounds, facilitated by the combination of triflic acid and fluoroalcohol. This metal-free method is complementary to conventional coupling reactions using metal catalysts and rea...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Naoko Takenaga, Toshitaka Shoji, Takayuki Menjo, Akiko Hirai, Shohei Ueda, Kotaro Kikushima, Tomonori Hanasaki, Toshifumi Dohi
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2019-10-01
Schriftenreihe:Molecules
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Online-Zugang:https://www.mdpi.com/1420-3049/24/21/3812
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