A Gallbladder‐Specific Hydrophobic Bile Acid‐FXR‐MUC1 Signaling Axis Mediates Cholesterol Gallstone Formation

Abstract Differences in the distribution of hydrophilic and hydrophobic bile acids (BA) are observed in mouse models of non‐alcoholic fatty liver disease (NAFLD) induced by a high‐fat‐cholesterol “Western‐style” diet (WD), and cholesterol gallstone disease (CGD) induced by a lithogenic diet. Despite...

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Autors principals:	Hongtan Chen, Xin Jiang, Yiqiao Li, Honggang Guo, Jianguo Wu, Sha Li, Fengling Hu, Guoqiang Xu
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2025-04-01
Col·lecció:	Advanced Science
Matèries:	caveolae cholesterol gallstone farnesoid X receptor hydrophobic bile acid pool protein kinase Cζ
Accés en línia:	https://doi.org/10.1002/advs.202401956
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