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Structural insights into MERS and SARS coronavirus membrane proteins

Abstract The membrane (M) protein of coronaviruses is essential for maintaining structural integrity during membrane virion budding and viral pathogenesis. Given its high conservation in lineages within the betacoronavirus genus, such as sarbecoviruses, the M protein presents as an attractive therap...

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Autori principali: Mandeep Kaur Mann, Yanting Yin, Simone Marsili, Jiexiong Xie, Jordi Doijen, Robyn Miller, Madison Piassek, Nick van den Broeck, Christopher Kinyanjui Kariuki, Heidi L. M. de Gruyter, Anouk A. Leijs, Eric J. Snijder, Martijn J. van Hemert, Ken Keustermans, Michiel Van Gool, Xiaodi Yu, Marnix van Loock, Anil Koul, Sujata Sharma, Ellen Van Damme, Pravien Abeywickrema
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2025-11-01
Serie:Communications Biology
Accesso online:https://doi.org/10.1038/s42003-025-09042-3
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