Phocaeicola vulgatus induces immunotherapy resistance in hepatocellular carcinoma via reducing indoleacetic acid production

Summary: Immunotherapy has made remarkable achievements in various cancers, but response rates in hepatocellular carcinoma (HCC) remain highly variable. Understanding mechanisms behind this heterogeneity and identifying responsive patients are urgent clinical challenges. In this study, the metagenom...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Cai-Ning Zhao, Shan-Shan Li, Thomas Yau, Wen-Qi Chen, Ren Ji, Xin-Yuan Guan, Feng-Ming (Spring) Kong
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2025-10-01
Цуврал:	Cell Reports Medicine
Нөхцлүүд:	gut microbiota immunotherapy immune checkpoint inhibitor liver cancer Phocaeicola vulgatus indoleacetic acid
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2666379125004434
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!