Plasma miR-134-5p: a candidate biomarker for predicting non-response to anti-TNF therapy in rheumatoid arthritis

IntroductionTumour necrosis factor inhibitors (anti-TNF agents) are a milestone in rheumatoid arthritis (RA) management, although 20-40% of RA patients do not achieve clinical remission. Identifying reliable biomarkers to predict the therapeutic response to anti-TNF agents remains an unmet clinical...

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Autors principals:	Arkaitz Mucientes, José Manuel Lisbona-Montañez, Patricia Ruiz-Limón, Rocío Bautista, Diego Lozano-Peral, Sara Manrique-Arija, Aimara García-Studer, Fernando Ortiz-Márquez, Natalia Mena-Vázquez, Antonio Fernández-Nebro
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-03-01
Col·lecció:	Frontiers in Immunology
Matèries:	anti-TNF biomarker inflammatory activity miRNA rheumatoid arthritis
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1783026/full
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