Effect of extracellular vesicles in remodeling the tumor microenvironment by DNMT1 downregulation for enhanced cancer immunotherapy

Background The efficacy of immunotherapy is often hindered by the suppression of immune responses via the tumor microenvironment (TME). The presence of cancer cells forces other proximal non-cancerous cells to support tumor growth and persistence. A clear example of this cancerous-to-non-cancerous c...

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Auteurs principaux: Sara Feola, Manlio Fusciello, Vincenzo Cerullo, John Bell, Firas Hamdan, Jacopo Chiaro, Yvonne Giannoula, Michaela Feodoroff, Gabriella Antignani, Salvatore Russo, Mikaela Grönholm, Julia Petryk, Virpi Stigzelius, Paolo Bottega, Justin Cerioni, Anja Thu Ha Dang, Carmine D’Amico, Carmen Caiazza, Federica D’Alessio, Milda Sakalauskaite, Carolina Ilkow
Format: Artigo
Langue:Inglês
Publié: BMJ Publishing Group 2025-11-01
Collection:Journal for ImmunoTherapy of Cancer
Accès en ligne:https://jitc.bmj.com/content/13/11/e012138.full
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