Single-cell sequencing highlights heterogeneity and malignant progression in actinic keratosis and cutaneous squamous cell carcinoma

Cutaneous squamous cell carcinoma (cSCC) is the second most frequent of the keratinocyte-derived malignancies with actinic keratosis (AK) as a precancerous lesion. To comprehensively delineate the underlying mechanisms for the whole progression from normal skin to AK to invasive cSCC, we performed s...

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Detalles Bibliográficos

Principais autores:	Dan-Dan Zou, Ya-Zhou Sun, Xin-Jie Li, Wen-Juan Wu, Dan Xu, Yu-Tong He, Jue Qi, Ying Tu, Yang Tang, Yun-Hua Tu, Xiao-Li Wang, Xing Li, Feng-Yan Lu, Ling Huang, Heng Long, Li He, Xin Li
Formato:	Artigo
Idioma:	Inglês
Publicado:	eLife Sciences Publications Ltd 2023-12-01
Series:	eLife
Assuntos:	single-cell transcriptome actinic keratosis cutaneous squamous cell carcinoma keratinocyte tumor microenvironment
Acceso en liña:	https://elifesciences.org/articles/85270
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