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The yeast Rab GTPase Ypt1 modulates unfolded protein response dynamics by regulating the stability of HAC1 RNA.

The unfolded protein response (UPR) is a conserved mechanism that mitigates accumulation of unfolded proteins in the ER. The yeast UPR is subject to intricate post-transcriptional regulation, involving recruitment of the RNA encoding the Hac1 transcription factor to the ER and its unconventional spl...

詳細記述

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書誌詳細
主要な著者: Nikoleta G Tsvetanova, Daniel P Riordan, Patrick O Brown
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2012-01-01
シリーズ:PLoS Genetics
オンライン・アクセス:http://europepmc.org/articles/PMC3406009?pdf=render
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