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Licensing instead of fueling: Glutamine synthetase promotes mitotic progression via a non-metabolic mechanism

A recent report published in Nature Metabolism identified that glutamine synthetase (GS), the only enzyme in mammals to produce glutamine from glutamate, can directly control cancer cell mitosis by governing the APC/C complex via a metabolism-independent mechanism. It reported that GS can directly i...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Zhao Jiang-Sha, Yang Jing, Lu Zhimin, Feng Yu-Xiong
Format: Artigo
Sprache:Inglês
Veröffentlicht: EDP Sciences 2023-01-01
Schriftenreihe:Visualized Cancer Medicine
Schlagworte:
Online-Zugang:https://vcm.edpsciences.org/articles/vcm/full_html/2023/01/vcm20220008/vcm20220008.html
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