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Duhuo Jisheng decoction alleviates neuroinflammation and neuropathic pain by suppressing microglial M1 polarization: a network pharmacology research

Abstract Background Neuropathic pain (NP) is the most prevalent form of chronic pain resulting from nerve damage or injury. Despite the widespread use of Duhuo Jisheng decoction (DHJSD) in traditional Chinese medicine (TCM) to treat chronic pain, the mechanism underlying its analgesic action remains...

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Main Authors: Chengcan Gao, Yulong Zhao, Tao Yang, Xu Gao, Chunyang Meng
Format: Artigo
Language:Inglês
Published: BMC 2023-08-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Duhuo Jisheng decoction
Network pharmacology
Neuropathic pain
Inflammation
Microglial
IL-17 signaling pathway
Online Access:https://doi.org/10.1186/s13018-023-04121-9
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