HDX-MS: An Analytical Tool to Capture Protein Motion in Action

Virtually all protein functions in the cell, including pathogenic processes, require coordinated motion of atoms or domains, i.e., conformational dynamics. Understanding protein dynamics is therefore critical both for drug development and to learn about the underlying molecular causes of many diseas...

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Bibliografski detalji

Glavni autori:	Dominic Narang, Cristina Lento, Derek J. Wilson
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2020-07-01
Serija:	Biomedicines
Teme:	hydrogen–deuterium exchange mass spectrometry HDX-MS protein dynamics protein folding and misfolding
Online pristup:	https://www.mdpi.com/2227-9059/8/7/224
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