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Direct visualization of protease action on collagen triple helical structure.

Enzymatic processing of extracellular matrix (ECM) macromolecules by matrix metalloproteases (MMPs) is crucial in mediating physiological and pathological cell processes. However, the molecular mechanisms leading to effective physiological enzyme-ECM interactions remain elusive. Only scant informati...

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Autores principales: Gabriel Rosenblum, Philippe E Van den Steen, Sidney R Cohen, Arkady Bitler, David D Brand, Ghislain Opdenakker, Irit Sagi
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2010-06-01
Colección:PLoS ONE
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20585385/pdf/?tool=EBI
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