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Arginine in the FARM and SARM: A Role in Chain-Length Determination for Arginine in the Aspartate-Rich Motifs of Isoprenyl Diphosphate Synthases from Mycobacterium tuberculosis

Isoprenyl chains are found in many important metabolites. These are derived from precursors of the appropriate length produced by isoprenyl diphosphate synthases (IDSs). The human pathogen Mycobacterium tuberculosis makes various isoprenoids/terpenoids, with important roles in their biosynthesis pla...

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Main Authors: Raimund Nagel, Jill A. Thomas, Faith A. Adekunle, Francis M. Mann, Reuben J. Peters
Format: Artigo
Language:Inglês
Published: MDPI AG 2018-10-01
Series:Molecules
Subjects:
terpene
isoprenoid
divalent metal co-factor ligation
Online Access:http://www.mdpi.com/1420-3049/23/10/2546
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