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Bioproduction of monoterpene indole alkaloids in a single cell factory

The de novo biosynthesis of vindoline and catharanthine, the direct precursors used for industrial production of the anti-cancer drug vinblastine, has been achieved in the yeast cell factory. To date, this is the longest natural product biosynthesis pathway that has been successfully transferred fro...

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Auteurs principaux: Jianping Huang, Shengxiong Huang
Format: Artigo
Langue:Inglês
Publié: KeAi Communications Co., Ltd. 2022-12-01
Collection:Engineering Microbiology
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Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2667370322000418
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