Sophoridine inhibits proliferation and migration by targeting PIM1 in breast cancer

Context Sophoridine, an alkaloid quinolizidine derived from Sophora flavescens Aiton (Fabaceae), has strong anti-tumor activity in a variety of malignancies. Nevertheless, the effects and underlying mechanism of sophoridine on breast cancer are not fully understood.Objective To identify the key targ...

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Detalhes bibliográficos

Principais autores:	Lu Chen, Yuting Xia, Liangliang Min, Yuqin Zhang, Da Huang, Yulu Zhang, Aihua You, Zhihua Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2025-12-01
Colecção:	Pharmaceutical Biology
Assuntos:	Breast cancer Sophoridine PIM1 ASK1/MAPK pathway
Acesso em linha:	https://www.tandfonline.com/doi/10.1080/13880209.2025.2537123
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