Synergistic effect of synthetic derivatives of 1,3,4-thiadiazole with amphotericin B in antifungal therapy

Abstract Amphotericin B (AmB) is a potent antifungal agent with minimal resistance among clinical isolates, but its use is limited by severe side effects. Reducing its toxicity through combination therapy with synergistic compounds is a promising strategy. This study investigates the antifungal pote...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Dominika Kubera, Adrianna Sławińska-Brych, Agnieszka Dróźdż, Alina Olender, Agnieszka Bogut, Arkadiusz Matwijczuk, Dariusz Karcz, Magdalena Kimsa-Dudek, Joanna Magdalena Gola, Celina Kruszniewska-Rajs, Jolanta Adamska, Magdalena Szukała, Wojciech Dąbrowski, Andrzej Stepulak, Mariusz Gagoś
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2025-05-01
Цуврал:	Scientific Reports
Нөхцлүүд:	Candida Antifungals Combination therapy Amphotericin B
Онлайн хандалт:	https://doi.org/10.1038/s41598-025-01075-2
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!