Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties
In mammalian cells, telomerase transcribes telomeres in large G-rich non-coding RNA, known as telomeric repeat-containing RNA (TERRA), which folds into noncanonical nucleic acid secondary structures called G-quadruplexes (G4s). Since TERRA G4 has been shown to be involved in telomere length and tran...
Furkejuvvon:
| Váldodahkkit: | , , , , , , , , , , , , , , |
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| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
MDPI AG
2022-04-01
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| Ráidu: | Pharmaceuticals |
| Fáttát: | |
| Liŋkkat: | https://www.mdpi.com/1424-8247/15/5/548 |
| Fáddágilkorat: |
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