Proteomic signatures of carotid plaque vulnerability: Proteolysis, inflammation, metabolic reprogramming, and lipid dysregulation

Background: Carotid plaque vulnerability is a current feature that aids in the decision-making for ischemic stroke risk. Proteomic analysis of plaque tissue can reveal molecular indicators of instability that complement imaging findings. We sought to identify a proteomic signature distinguishing vul...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Camilo Polania Sandoval, MD, James F. Meschia, MD, Mercedes Prudencio, PhD, Tania Gendron, PhD, Christopher Jacobs, MD, Richard D. Beegle, MD, Sukhwinder J.S. Sandhu, MD, Kiran K. Mangalaparthi, PhD, Jaeyun Sung, PhD, Xiaowei Zhao, PhD, Aziza Nassar, MD, MPH, MBA, Houssam Farres, MD, Leonard Petrucelli, PhD, Akhilesh Pandey, MD, PhD, Young Erben, MD
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2026-01-01
Serier:	JVS - Vascular Science
Fag:	Carotid artery disease Stroke Risk stratification Vulnerable features Proteomics
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2666350325001257
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