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Disease Transmission by Misfolded Prion-Protein Isoforms, Prion-Like Amyloids, Functional Amyloids and the Central Dogma

In 1982, the term “prions” (proteinaceous infectious particles) was coined to specify a new principle of infection. A misfolded isoform of a cellular protein has been described as the causative agent of a fatal neurodegenerative disease. At the beginning of prion research scientists assumed that the...

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Autor principal: Martin L. Daus
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2016-01-01
coleção:Biology
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Acesso em linha:http://www.mdpi.com/2079-7737/5/1/2
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