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Preserved white matter integrity is a promising indicator of cognitive resilience in Parkinson’s disease

Abstract Cognitive and motor impairment in Parkinson’s disease (PD) is linked to white matter integrity, yet the prognostic utility of white matter-derived imaging metrics for predicting cognitive and motor decline remains underexplored. Leveraging longitudinal clinical and neuroimaging data from th...

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Principais autores: Zhichun Chen, Weiting Tang, Yuxuan Shi, Sheng Hu, Bin Chen, Jindong Ding Petersen, Binwen Huang, Jun Liu, Yong You
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-12-01
Serier:Scientific Reports
Fag:
Parkinson’s disease
White matter integrity
Cognitive function
Motor decline
Cognitive resilience
Online adgang:https://doi.org/10.1038/s41598-025-30478-4
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