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Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast

Summary: CDH1 and PIK3CA are the two most frequently mutated genes in invasive lobular carcinoma (ILC) of the breast. Transcription profiling has identified molecular subtypes for ILC, one of which, immune-related (IR), is associated with gene expression linked to lymphocyte and macrophage infiltrat...

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Principais autores: Yeji An, Jessica R. Adams, Daniel P. Hollern, Anthony Zhao, Stephen G. Chang, Miki S. Gams, Philip E.D. Chung, Xiaping He, Rhea Jangra, Juhi S. Shah, Joanna Yang, Lauren A. Beck, Nandini Raghuram, Katelyn J. Kozma, Amanda J. Loch, Wei Wang, Cheng Fan, Susan J. Done, Eldad Zacksenhaus, Cynthia J. Guidos, Charles M. Perou, Sean E. Egan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018-10-01
Colecção:Cell Reports
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211124718315018
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