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Gene coexpression networks reveal a broad role for lncRNAs in inflammatory bowel disease

The role of long noncoding RNAs (lncRNAs) in disease is incompletely understood, but their regulation of inflammation is increasingly appreciated. We addressed the extent of lncRNA involvement in inflammatory bowel disease (IBD) using biopsy-derived RNA-sequencing data from a large cohort of deeply...

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Principais autores: John L. Johnson, Davit Sargsyan, Eric M. Neiman, Amy Hart, Aleksandar Stojmirovic, Roman Kosoy, Haritz Irizar, Mayte Suárez-Fariñas, Won-Min Song, Carmen Argmann, Stefan Avey, Liraz Shmuel-Galia, Tim Vierbuchen, Gerold Bongers, Yu Sun, Leonard Edelstein, Jacqueline Perrigoue, Jennifer E. Towne, Aisling O’Hara Hall, Katherine A. Fitzgerald, Kasper Hoebe
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical investigation 2024-02-01
Serier:JCI Insight
Fag:
Gastroenterology
Immunology
Online adgang:https://doi.org/10.1172/jci.insight.168988
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