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Chronic alcohol exposure contributes to postoperative cognitive dysfunction via NR2B upregulation in the hippocampus of adult mice

Abstract Postoperative cognitive dysfunction (POCD) is a common perioperative complication of the central nervous system, and patients with chronic alcohol exposure frequently require surgery under anesthesia. However, the contribution of chronic alcohol exposure to POCD and its underlying mechanism...

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Principais autores: Linhui Ma, Shuai Li, Wei Dong, Jie Wan, Zhichao Li, Chudi Zhang, Xinjie Zhou, Zhifan Wang, Chenghua Zhou, Yuqing Wu, Hui Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2026-05-01
coleção:Translational Psychiatry
Acesso em linha:https://doi.org/10.1038/s41398-026-04087-2
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