Cholesterol and oxysterol metabolism and subcellular distribution in macrophage foam cells: accumulation of oxidized esters in lysosomes

Cholesterol- and cholesteryl ester-rich macrophage foam cells, characteristic of atherosclerotic lesions, are often generated in vitro using oxidized low density lipoprotein (OxLDL). However, relatively little is known of the nature and extent of sterol deposition in these cells or of its relationsh...

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Detalhes bibliográficos

Principais autores:	Andrew J. Brown, Erin L. Mander, Ingrid C. Gelissen, Leonard Kritharides, Roger T. Dean, Wendy Jessup
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2000-02-01
coleção:	Journal of Lipid Research
Assuntos:	atherosclerosis macrophage foam cell cholesterol 7-ketocholesterol low density lipoprotein
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0022227520320563
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