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Platinum and Taxane Based Adjuvant and Neoadjuvant Chemotherapy in Early Triple-Negative Breast Cancer: A Narrative Review

Platinum (Pt) derivatives such as cisplatin and carboplatin are the class of drugs with proven activity against triple-negative breast cancer (TNBC). This is due to the ability of Pt compounds to interfere with the DNA repair mechanisms of the neoplastic cells. Taxanes have been efficacious against...

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Principais autores: Hao Tian, Dandan Ma, Xuanni Tan, Wenting Yan, Xiujuan Wu, Cheng He, Ling Zhong, Yan Zhang, Bingjie Yu, Yi Zhang, Xiaowei Qi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-12-01
coleção:Frontiers in Pharmacology
Assuntos:
adjuvant chemotherapy
neoadjuvant therapy
platinum
taxane
triple negative breast cancer
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2021.770663/full
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