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GPR137-RAB8A activation promotes ovarian cancer development via the Hedgehog pathway

Abstract Background Ovarian cancer (OC) progression is one of the commonest cause of female cancer death. While treatments in clinic includes primary surgery and targeted chemotherapy, curative and survival trends in OC have not significantly improved. Thus, further investigation of the mechanisms r...

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Hauptverfasser: Chao Tang, Lin Li, Chongying Zhu, Qiang Xu, Zihao An, Shouying Xu, Chao Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2025-01-01
Schriftenreihe:Journal of Experimental & Clinical Cancer Research
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Online-Zugang:https://doi.org/10.1186/s13046-025-03275-0
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