Carnosic Acid Directly Targets STING C‐Terminal Tail to Improve STING‐Mediated Inflammatory Diseases

Abstract cGAS (cyclic GMP‐AMP synthase)‐STING (stimulator of interferon genes) signaling plays a vital role in innate immunity, while its deregulation may lead to a wide variety of autoinflammatory and autoimmune diseases. It is essential to identify specifically effective lead compounds to inhibit...

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Detalhes bibliográficos

Principais autores:	Wenqing Mu, Guang Xu, Ling Li, Jincai Wen, Ye Xiu, Jia Zhao, Tingting Liu, Ziying Wei, Wei Luo, Huijie Yang, Zhixin Wu, Xiaoyan Zhan, Xiaohe Xiao, Zhaofang Bai
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-04-01
coleção:	Advanced Science
Assuntos:	carnosic acid cGAS‐STING inflammatory responses STING inhibitors Trex1 deficiency
Acesso em linha:	https://doi.org/10.1002/advs.202417686
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