Source control within 12 h attenuates lung injury and systemic bacterial burden in a rat model of polymicrobial abdominal sepsis (cecal ligation and puncture)

Abstract Background Early and adequate source control (SC) is a cornerstone of sepsis management, yet experimental data linking delays in SC to bacterial dissemination and remote organ injury remain limited. We aimed to determine how the timing of surgical SC after polymicrobial abdominal sepsis inf...

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Principais autores:	Maria Luisa Martinez, Eva Torrents, Marta Camprubí-Rimblas, Josep Bringué, Adrian Ceccato, Ricard Ferrer, Antonio Artigas, Raquel Guillamat-Prats
Formato:	Artigo
Idioma:	Inglês
Publicado em:	SpringerOpen 2026-07-01
Colecção:	Intensive Care Medicine Experimental
Assuntos:	Sepsis Source control Cecal ligation and puncture Inflammation Lung injury Experimental model
Acesso em linha:	https://doi.org/10.1186/s40635-026-00941-1
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