Failure of intrathecal allogeneic mesenchymal stem cells to halt progressive demyelination in two boys with cerebral adrenoleukodystrophy

Abstract Cerebral adrenoleukodystrophy is an inflammatory demyelinating condition that is the result of a mutation in the X‐linked ABCD1 gene, a peroxisomal very long chain fatty acid transporter. Although mutations in this gene result in adrenal insufficiency in the majority of affected individuals...

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Principais autores:	Ashish Gupta, Paul J. Orchard, Weston P. Miller, Dave R. Nascene, Gerald V. Raymond, Daniel J. Loes, David H. McKenna, Troy C. Lund
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2020-05-01
coleção:	Stem Cells Translational Medicine
Assuntos:	adrenoleukodystrophy autoimmune demyelination inflammation mesenchymal stem cells
Acesso em linha:	https://doi.org/10.1002/sctm.19-0304
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