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Senolytic effects of first and second generation BCL-xL/BCL-2 dual degraders

The aim. To conduct a literature review of current data on the senolytic effects of dual BCL-xL/BCL-2 degraders, including available molecules, their mechanism of action, efficacy, and safety.Materials and Methods. Literature search was performed in PubMed, Science Direct, and SciELO databases using...

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Bibliografiske detaljer
Principais autores: E. S. Berezhnaya, A. V. Savustyanenko
Format: Artigo
Sprog:Russo
Udgivet: Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute 2026-04-01
Serier:Фармация и фармакология (Пятигорск)
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Online adgang:https://www.pharmpharm.ru/jour/article/view/1862
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